SCI
16August
Well-differentiatedBronchopulmonaryNeuroendocrineTumors:MoreThanOneEntity
MedardF.M.vandenBroek,SonjaLevy,WienekeA.Buikhuisen,KimDijke,KoenJ.Hartemink,RachelS.vanLeeuwaarde,MennoR.Vriens,MargotE.T.Tesselaar,GerlofD.Valk
Correspondenceto
.d.valk
umcutrecht.nlBackground背景
Untilnow,well-differentiatedbronchopulmonaryneuroendocrinetumors(bpNET)occurringeithersporadically(sp-bpNET)orinthecontextofMultipleEndocrineNeoplasiaType1(MEN1)andDiffuseIdiopathicPulmonaryNeuroendocrineCellHyperplasia(DIPNECH)areregardedassimilarentities.However,incontrasttosp-bpNET:MEN1-relatedandDIPNECH-relatedbpNETrarelymetastasizeorleadtobpNET-relateddeath.
到目前为止，高分化支气管肺神经内分泌肿瘤(bpNET)囊括的偶发性高分化支气管肺神经内分泌肿瘤（spbpNET）或多发性高分化支气管肺神经内分泌肿瘤1型（MEN1）及弥漫性特发性肺神经内分泌细胞增生（DIPNECH）被认为是类似的实体。然而，与sp-bpNET相反：MEN1相关和DIPNECH相关的bpNET很少转移或导致bpNE-相关死亡。
Aims目的
Todescribeand
